Ivermectin is a medication that is primarily used to treat certain parasitic infections. It is available in both oral and topical forms and can be prescribed for a wide range of conditions, including head lice, scabies, and river blindness. The oral form of ivermectin is also used to prevent heartworm disease in dogs and cats. In recent times, Ivermectin has been in the spotlight for its potential use as a treatment for COVID-19.

Uses of Ivermectin

Ivermectin is primarily used as an antiparasitic medication. The drug is used to treat a variety of parasitic infections, including:

• Scabies: A condition caused by the mite Sarcoptes scabiei, which results in itching and skin irritation.
• Head lice: An infection caused by the lice Pediculus humanus capitis, which results in itching and scratching of the scalp.
• River blindness: A condition caused by the parasitic worm Onchocerca volvulus, which results in severe itching and skin thickening, as well as blindness.
• Strongyloidiasis: A parasitic infection caused by the nematode Strongyloides stercoralis, which can cause abdominal pain, diarrhea, and other symptoms.
• Ascariasis: A parasitic infection caused by the nematode Ascaris lumbricoides, which can cause abdominal pain, diarrhea, and other symptoms.

Benefits of Ivermectin

Ivermectin is a very effective medication for treating parasitic infections. The drug works by paralyzing the parasites, which makes them easier to remove. It also kills the parasites and helps to prevent them from spreading. Ivermectin is also considered a safe medication, with few side effects. The oral form of ivermectin is well-tolerated by most patients, and the topical form is generally well-tolerated by most people as well.

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Recently, it has been studied and some scientists believed that the drug can be used to treat COVID-19, Some small studies and observational studies have shown that Ivermectin may be effective in reducing the severity of COVID-19 symptoms and preventing hospitalization, further research and clinical trials are needed to confirm these findings and to determine appropriate dosing regimens.

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Side Effects of Ivermectin

Like all medications, ivermectin can cause side effects in some people. The most common side effects of the drug are mild and include:

• Headache
• Dizziness
• Nausea
• Stomach upset

In rare cases, more serious side effects can occur, such as allergic reactions, which can be characterized by difficulty breathing, hives, and swelling of the face, lips, tongue, or throat. If you experience any of these symptoms, it is important to seek medical attention immediately.

How Ivermectin Works

Ivermectin works by binding to a specific protein called the glutamate-gated chloride channels (GluCls) present in the nerve cells of invertebrates, including many parasites. This binding causes an influx of chloride ions into the cells, which leads to the paralysis and death of the parasites. The binding also causes an inhibition of neurotransmitter release, which further contributes to the paralysis of the parasites.

In the case of heartworm prevention, ivermectin works by killing the immature forms of the heartworm (microfilariae).

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